Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC3851881 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zhang Yunpeng Y Fan Huihui H Xu Juan J Xiao Yun Y Xu Yanjun Y Li Yixue Y Li Xia X
Scientific reports 20131205
Connections between inflammation and diseases are suggested important in understanding the genetic mechanisms of diseases. However, studies on the functional cross-links between inflammation and disease genes are still in their early stages. We integrated the protein-protein interaction (PPI), inflammation genes, and gene-disease associations to construct a disease-inflammation network (DIN). We found that nodes, which are both inflammation and disease genes (namely inter-genes), are topological ...[more]