Dynamics of adaptive alleles in divergently selected body weight lines of chickens.

ABSTRACT: By studying genomic changes over time in populations subjected to strong artificial directional selection, we can gain insights to the dynamics of beneficial alleles originating from the founder population or emerging as novel mutations undergoing ongoing selection. The Virginia lines are a chicken resource population generated by long-term bi-directional, single-trait selection for juvenile body weight. We studied genome-wide allele frequency changes from generation 40 to 53 using genome-wide genotypes from directional and relaxed selection lines. Overall, there were small changes in allele frequencies at individual loci over the studied time period; but, on average, the changes were greater in lines with larger phenotypic changes. This is consistent with previous findings that much of th

SUBMITTER: Pettersson ME 

PROVIDER: S-EPMC3852392 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature