Association of CILP2 and ACE gene polymorphisms with cardiovascular risk factors in Slovak midlife women.
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ABSTRACT:
SUBMITTER: Luptakova L
PROVIDER: S-EPMC3854549 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
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Association of CILP2 and ACE gene polymorphisms with cardiovascular risk factors in Slovak midlife women.
Luptáková Lenka L Benčová Dominika D Siváková Daniela D Cvíčelová Marta M
BioMed research international 20131120
The aim of this study is to assess the association of two polymorphisms, the cartilage intermediate layer protein 2 (CILP2) G/T and angiotensin converting enzyme (ACE) I/D, with blood pressure and anthropometrical and biochemical parameters related to the development of cardiovascular disease. The entire study sample comprised 341 women ranging in age from 39 to 65 years. The CILP2 genotypes were determined by PCR-RFLP and the ACE genotypes by PCR. The Bonferroni pairwise comparisons showed the ...[more]
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