Ontology highlight
ABSTRACT:
SUBMITTER: Carvalho L
PROVIDER: S-EPMC3855595 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PloS one 20131206 12
Biological sequences may contain patterns that signal important biomolecular functions; a classical example is regulation of gene expression by transcription factors that bind to specific patterns in genomic promoter regions. In motif discovery we are given a set of sequences that share a common motif and aim to identify not only the motif composition, but also the binding sites in each sequence of the set. We propose a new centroid estimator that arises from a refined and meaningful loss functi ...[more]