Ontology highlight
ABSTRACT:
SUBMITTER: Shala A
PROVIDER: S-EPMC3855734 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Shala Agnesa A Patel Kevin H KH Golemi-Kotra Dasantila D Audette Gerald F GF
Acta crystallographica. Section F, Structural biology and crystallization communications 20131129 Pt 12
The response-regulatory protein LytR belongs to a family of transcription factors involved in the regulation of important virulence factors in pathogenic bacteria. The protein consists of a receiver domain and an effector domain, which play an important role in controlled cell death and lysis. The LytR receiver domain (LytR(N)) has been overexpressed, purified and crystallized using the sitting-drop and hanging-drop vapour-diffusion methods. The crystals grew as needles, with unit-cell parameter ...[more]