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Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates.

ABSTRACT: A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.

SUBMITTER: Lackner GL

PROVIDER: S-EPMC3856227 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates.

Lackner Gregory L GL Quasdorf Kyle W KW Overman Larry E LE

Journal of the American Chemical Society 20131002 41

A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported. ...[more]

PMID: 24074152

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