Vitamin B12 supplementation in treating major depressive disorder: a randomized controlled trial.
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ABSTRACT:
SUBMITTER: Syed EU
PROVIDER: S-EPMC3856388 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Vitamin B12 supplementation in treating major depressive disorder: a randomized controlled trial.
Syed Ehsan Ullah EU Wasay Mohammad M Awan Safia S
The open neurology journal 20131115
<h4>Background/objective</h4>Recent literature has identified links between vitamin B12 deficiency and depression.We compared the clinical response of SSRI-monotherapy with that of B12-augmentation in a sample of depressed patients with low normal B12 levels who responded inadequately to the first trial with the SSRIs.<h4>Methods</h4>Patients with depression and low normal B12 levels were randomized to a control arm (antidepressant only) or treatment arm (antidepressants and injectable vitamin B ...[more]
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