Ontology highlight
ABSTRACT:
SUBMITTER: Kashiwagi S
PROVIDER: S-EPMC3859633 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Kashiwagi Satoshi S Yuan Jianping J Forbes Benjamin B Hibert Mathew L ML Lee Eugene L Q EL Whicher Laura L Goudie Calum C Yang Yuan Y Chen Tao T Edelblute Beth B Collette Brian B Edington Laurel L Trussler James J Nezivar Jean J Leblanc Pierre P Bronson Roderick R Tsukada Kosuke K Suematsu Makoto M Dover Jeffrey J Brauns Timothy T Gelfand Jeffrey J Poznansky Mark C MC
PloS one 20131211 12
Safe and effective immunologic adjuvants are often essential for vaccines. However, the choice of adjuvant for licensed vaccines is limited, especially for those that are administered intradermally. We show that non-tissue damaging, near-infrared (NIR) laser light given in short exposures to small areas of skin, without the use of additional chemical or biological agents, significantly increases immune responses to intradermal influenza vaccination without augmenting IgE. The NIR laser-adjuvante ...[more]