An automated blur detection method for histological whole slide imaging.
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ABSTRACT:
SUBMITTER: Moles Lopez X
PROVIDER: S-EPMC3862630 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
An automated blur detection method for histological whole slide imaging.
Moles Lopez Xavier X D'Andrea Etienne E Barbot Paul P Bridoux Anne-Sophie AS Rorive Sandrine S Salmon Isabelle I Debeir Olivier O Decaestecker Christine C
PloS one 20131213 12
Whole slide scanners are novel devices that enable high-resolution imaging of an entire histological slide. Furthermore, the imaging is achieved in only a few minutes, which enables image rendering of large-scale studies involving multiple immunohistochemistry biomarkers. Although whole slide imaging has improved considerably, locally poor focusing causes blurred regions of the image. These artifacts may strongly affect the quality of subsequent analyses, making a slide review process mandatory. ...[more]
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