Ontology highlight
ABSTRACT:
SUBMITTER: Melton PE
PROVIDER: S-EPMC3865281 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Melton Phillip E PE Carless Melanie A MA Curran Joanne E JE Dyer Thomas D TD Göring Harald H H HH Kent Jack W JW Drigalenko Eugene E Johnson Matthew P MP Maccluer Jean W JW Moses Eric K EK Comuzzie Anthony G AG Mahaney Michael C MC O'Leary Daniel H DH Blangero John J Almasy Laura L
Circulation. Cardiovascular genetics 20130313 2
BACKGROUND- Intima-media thickness (IMT) of the common and internal carotid arteries is an established surrogate for atherosclerosis and predicts risk of stroke and myocardial infarction. Often IMT is measured as the average of these 2 arteries; yet, they are believed to result from separate biological mechanisms. The aim of this study was to conduct a family-based genome-wide association study (GWAS) for IMT to identify polymorphisms influencing IMT and to determine if distinct carotid artery s ...[more]