Ontology highlight
ABSTRACT:
SUBMITTER: Dame RT
PROVIDER: S-EPMC3865359 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Dame Remus T RT Hall Michael A MA Wang Michelle D MD
Chembiochem : a European journal of chemical biology 20130902 15
The genome of bacteria is organized and compacted by the action of nucleoid-associated proteins. These proteins are often present in tens of thousands of copies and bind with low specificity along the genome. DNA-bound proteins thus potentially act as roadblocks to the progression of machinery that moves along the DNA. In this study, we have investigated the effect of histone-like protein from strain U93 (HU), one of the key proteins involved in shaping the bacterial nucleoid, on DNA helix stabi ...[more]