Ontology highlight
ABSTRACT:
SUBMITTER: Song P
PROVIDER: S-EPMC3866050 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Song Pingfang P Rekow Stephen S SS Singleton Corey-Ayne CA Sekhon Harmanjatinder S HS Dissen Gregory A GA Zhou Minerva M Campling Barbara B Lindstrom Jon J Spindel Eliot R ER
Journal of neurochemistry 20130625 4
Synthesis of acetylcholine (ACh) by non-neuronal cells is now well established and plays diverse physiologic roles. In neurons, the Na(+) -dependent, high affinity choline transporter (CHT1) is absolutely required for ACh synthesis. In contrast, some non-neuronal cells synthesize ACh in the absence of CHT1 indicating a fundamental difference in ACh synthesis compared to neurons. The aim of this study was to identify choline transporters, other than CHT1, that play a role in non-neuronal ACh synt ...[more]