Ontology highlight
ABSTRACT:
SUBMITTER: Liang S
PROVIDER: S-EPMC3867632 | biostudies-literature | 2009 Aug
REPOSITORIES: biostudies-literature
Liang Shide S Wang Guangce G Zhou Yaoqi Y
Proteins 20090801 2
How to refine a near-native structure to make it closer to its native conformation is an unsolved problem in protein-structure and protein-protein complex-structure prediction. In this article, we first test several scoring functions for selecting locally resampled near-native protein-protein docking conformations and then propose a computationally efficient protocol for structure refinement via local resampling and energy minimization. The proposed method employs a statistical energy function b ...[more]