Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.
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ABSTRACT:
SUBMITTER: Moore LK
PROVIDER: S-EPMC3872062 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Diamond-lipid hybrids enhance chemotherapeutic tolerance and mediate tumor regression.
Moore Laura K LK Chow Edward K EK Osawa Eiji E Bishop J Michael JM Ho Dean D
Advanced materials (Deerfield Beach, Fla.) 20130415 26
Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers. ...[more]
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