Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor.
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ABSTRACT:
SUBMITTER: Funabashi M
PROVIDER: S-EPMC3873198 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor.
Funabashi Masanori M Baba Satoshi S Takatsu Toshio T Kizuka Masaaki M Ohata Yasuo Y Tanaka Masahiro M Nonaka Koichi K Spork Anatol P AP Ducho Christian C Chen Wei-Chen Leyla WC Van Lanen Steven G SG
Angewandte Chemie (International ed. in English) 20130906 44
Rise and shine: Using a gene-targeting approach aimed at identifying potential L-threonine:uridine-5'-transaldolases that catalyze the formation of (5'S,6'S)-C-glycyluridine, a new bacterial translocase I inhibitor was discovered from an actinomycete following fermentation optimization. ...[more]
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