The yeast cell-cycle network is robustly designed.
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ABSTRACT:
SUBMITTER: Li F
PROVIDER: S-EPMC387325 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Publications
The yeast cell-cycle network is robustly designed.
Li Fangting F Long Tao T Lu Ying Y Ouyang Qi Q Tang Chao C
Proceedings of the National Academy of Sciences of the United States of America 20040322 14
The interactions between proteins, DNA, and RNA in living cells constitute molecular networks that govern various cellular functions. To investigate the global dynamical properties and stabilities of such networks, we studied the cell-cycle regulatory network of the budding yeast. With the use of a simple dynamical model, it was demonstrated that the cell-cycle network is extremely stable and robust for its function. The biological stationary state, the G1 state, is a global attractor of the dyn ...[more]
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