Ontology highlight
ABSTRACT:
SUBMITTER: Deryusheva S
PROVIDER: S-EPMC387330 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Deryusheva Svetlana S Gall Joseph G JG
Proceedings of the National Academy of Sciences of the United States of America 20040324 14
Cajal bodies (CBs) are complex organelles found in the nuclei of a wide variety of organisms, including vertebrates, invertebrates, plants, and yeast. In most cell types CBs are <1 microm in diameter, severely limiting the range of experimental observations that can be made on them. By contrast, CBs in the amphibian oocyte nucleus (also called the germinal vesicle) are 2-10 microm in diameter. We have taken advantage of this large size to carry out kinetic studies on coilin, a protein that is sp ...[more]