Ontology highlight
ABSTRACT:
SUBMITTER: Raissi AJ
PROVIDER: S-EPMC3873869 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Molecular and cellular neurosciences 20130910
While numerous recent advances have contributed to our understanding of excitatory synapse formation, the processes that mediate inhibitory synapse formation remain poorly defined. Previously, we discovered that RNAi-mediated knockdown of a Class 4 Semaphorin, Sema4D, led to a decrease in the density of inhibitory synapses without an apparent effect on excitatory synapse formation. Our current work has led us to new insights about the molecular mechanisms by which Sema4D regulates GABAergic syna ...[more]