Ontology highlight
ABSTRACT:
SUBMITTER: Petereit DG
PROVIDER: S-EPMC3874556 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Petereit Daniel G DG Hahn L Jennifer LJ Kanekar Shalini S Boylan Amy A Bentzen Søren M SM Ritter Mark M Moser Amy R AR
Frontiers in oncology 20131230
<h4>Purpose</h4>To identify sequence variants of the ataxia telangiectasia mutated (ATM) gene and establish their prevalence rate among American Indian (AI) as compared with non-AI cancer patients.<h4>Materials and methods</h4>DNA was isolated from blood samples collected from 100 AI and 100 non-AI cancer patients undergoing radiation therapy, and a blinded assessment of the ATM sequence was conducted. Quantitative PCR assessment of copy number for each exon was also performed. The main outcome ...[more]