Ontology highlight
ABSTRACT:
SUBMITTER: Li CI
PROVIDER: S-EPMC3874726 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
International journal of computational biology and drug design 20130930 4
Sample size determination is an important issue in the experimental design of biomedical research. Because of the complexity of RNA-seq experiments, however, the field currently lacks a sample size method widely applicable to differential expression studies utilising RNA-seq technology. In this report, we propose several methods for sample size calculation for single-gene differential expression analysis of RNA-seq data under Poisson distribution. These methods are then extended to multiple gene ...[more]