Ontology highlight
ABSTRACT:
SUBMITTER: Shabbir SH
PROVIDER: S-EPMC3875369 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Shabbir Shagufta H SH Cleland Megan M MM Goldman Robert D RD Mrksich Milan M
Biomaterials 20131121 5
Significant efforts have addressed the role of vimentin intermediate filaments (VIF) in cell motility, shape, adhesion and their connections to microfilaments (MF) and microtubules (MT). The present work uses micropatterned substrates to control the shapes of mouse fibroblasts and demonstrates that the cytoskeletal elements are dependent on each other and that unlike MF, VIF are globally controlled. For example, both square and circle shaped cells have a similar VIF distribution while MF distrib ...[more]