Ontology highlight
ABSTRACT:
SUBMITTER: Shafie NH
PROVIDER: S-EPMC3876062 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20131202 12
Inositol hexaphosphate (IP6), or phytic acid is a natural dietary ingredient and has been described as a "natural cancer fighter", being an essential component of nutritional diets. The marked anti-cancer effect of IP6 has resulted in our quest for an understanding of its mechanism of action. In particular, our data provided strong evidence for the induction of apoptotic cell death, which may be attributable to the up-regulation of Bax and down-regulation of Bcl-xl in favor of apoptosis. In addi ...[more]