The contribution of diet and genotype to iron status in women: a classical twin study.
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ABSTRACT:
SUBMITTER: Fairweather-Tait SJ
PROVIDER: S-EPMC3876997 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
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The contribution of diet and genotype to iron status in women: a classical twin study.
Fairweather-Tait Susan J SJ Guile Geoffrey R GR Valdes Ana M AM Wawer Anna A AA Hurst Rachel R Skinner Jane J Macgregor Alexander J AJ
PloS one 20131231 12
This is the first published report examining the combined effect of diet and genotype on body iron content using a classical twin study design. The aim of this study was to determine the relative contribution of genetic and environmental factors in determining iron status. The population was comprised of 200 BMI- and age-matched pairs of MZ and DZ healthy twins, characterised for habitual diet and 15 iron-related candidate genetic markers. Variance components analysis demonstrated that the herit ...[more]
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