Ontology highlight
ABSTRACT:
SUBMITTER: Saha A
PROVIDER: S-EPMC3877685 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Saha Ashis A Tan Aik Choon AC Kang Jaewoo J
PloS one 20140101 1
Genes act in concert via specific networks to drive various biological processes, including progression of diseases such as cancer. Under different phenotypes, different subsets of the gene members of a network participate in a biological process. Single gene analyses are less effective in identifying such core gene members (subnetworks) within a gene set/network, as compared to gene set/network-based analyses. Hence, it is useful to identify a discriminative classifier by focusing on the subnet ...[more]