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Teaching an old dog new tricks: drug repositioning in small cell lung cancer.


ABSTRACT: Jahchan and colleagues report the use of a biostatistical analysis to identify effective therapeutics for small cell lung cancer (SCLC). Their results reveal a new use for the tricyclic antidepressant imipramine in SCLC and shed light on the therapeutic potential of drug repositioning in cancer and other diseases.

SUBMITTER: Wang J 

PROVIDER: S-EPMC3878064 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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Teaching an old dog new tricks: drug repositioning in small cell lung cancer.

Wang Jing J   Byers Lauren Averett LA  

Cancer discovery 20131201 12


Jahchan and colleagues report the use of a biostatistical analysis to identify effective therapeutics for small cell lung cancer (SCLC). Their results reveal a new use for the tricyclic antidepressant imipramine in SCLC and shed light on the therapeutic potential of drug repositioning in cancer and other diseases. ...[more]

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