Ontology highlight
ABSTRACT:
SUBMITTER: Makara JK
PROVIDER: S-EPMC3878388 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Makara Judit K JK Magee Jeffrey C JC
Neuron 20131201 6
The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We f ...[more]