Ontology highlight
ABSTRACT:
SUBMITTER: Navarro-Gonzalez I
PROVIDER: S-EPMC3879275 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Navarro-González Inmaculada I Pérez-Sánchez Horacio H Martín-Pozuelo Gala G García-Alonso Javier J Periago Maria Jesús MJ
PloS one 20140102 1
The hypocholesterolemic effect of tomato juice has been investigated in an intervention study with rats, along with the possible inhibition effect of bioactive tomato compounds binding to the HMGCR enzyme. Two experimental groups (n = 8 Sprague-Dawley rats) were fed ad libitum for five weeks, with water or tomato juice provided to the control and intervention groups, respectively. Total, LDL and HDL cholesterol, and total triglycerides were analysed in plasma, and the lycopene content and the ex ...[more]