Ontology highlight
ABSTRACT:
SUBMITTER: Lease N
PROVIDER: S-EPMC3880617 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Lease Nicholas N Vasilevski Vadim V Carreira Monica M de Almeida Andreia A Sanaú Mercedes M Hirva Pipsa P Casini Angela A Contel María M
Journal of medicinal chemistry 20130702 14
A series of gold(III) and palladium(II) heterometallic complexes with new iminophosphorane ligands derived from ferrocenylphosphanes [{Cp-P(Ph2)═N-Ph}2Fe] (1), [{Cp-P(Ph2)═N-CH2-2-NC5H4}2Fe] (2), and [{Cp-P(Ph2)═N-CH2-2-NC5H4}Fe(Cp)] (3) have been synthesized and structurally characterized. Ligands 2 and 3 afford stable coordination complexes [AuCl2(3)]ClO4, [{AuCl2}2(2)](ClO4)2, [PdCl2(3)], and [{PdCl2}2(2)]. The complexes have been evaluated for their antiproliferative properties in human ovar ...[more]