Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans.
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ABSTRACT:
SUBMITTER: Salzberg Y
PROVIDER: S-EPMC3881433 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Publications
Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans.
Salzberg Yehuda Y Díaz-Balzac Carlos A CA Ramirez-Suarez Nelson J NJ Attreed Matthew M Tecle Eillen E Desbois Muriel M Kaprielian Zaven Z Bülow Hannes E HE
Cell 20131001 2
Sensory dendrites depend on cues from their environment to pattern their growth and direct them toward their correct target tissues. Yet, little is known about dendrite-substrate interactions during dendrite morphogenesis. Here, we describe MNR-1/menorin, which is part of the conserved Fam151 family of proteins and is expressed in the skin to control the elaboration of "menorah"-like dendrites of mechanosensory neurons in Caenorhabditis elegans. We provide biochemical and genetic evidence that M ...[more]
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