Ontology highlight
ABSTRACT:
SUBMITTER: Deniz E
PROVIDER: S-EPMC3881542 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Deniz Engin E Jonas Stephan S Khokha Mustafa M Choma Michael A MA
Optics letters 20120701 14
The genetic basis of congenital heart disease is yet to be defined, and the interactions between the malformed heart and biomechanical cardiac performance remain poorly understood. Functional optical imaging enables detailed biomechanical phenotyping of cardiac dysfunction in small animal models, which in turn enables specific gene-phenotype relationship. We have developed a new microangiography technique based on flow imaging using endogenous hemoglobin contrast enabling in vivo assessment and ...[more]