Dataset Information

Relevant baseline characteristics for describing patients with knee osteoarthritis: results from a Delphi survey.

ABSTRACT:

Background

Inclusion/exclusion criteria and baseline characteristics are essential for assessing the applicability of trial results to a given patient and the comparability of study populations for meta-analyses. This Delphi survey aimed to generate a set of baseline characteristics for describing patients with knee osteoarthritis enrolled in clinical studies.

Methods

Survey participants comprised clinical experts (n = 23; mean age 54 y; from 4 continents) that had authored at least two randomized trials on knee osteoarthritis. First, given a prepared list of baseline patient characteristics, the experts were asked to add characteristics they considered important for assessing comparability of patient populations in different trials that evaluated the efficacy of non-surgical interventions for treating knee osteoarthritis. Next, they were asked to rate the importance of each characteristic, on a scale of 0 (not important) to 10 (highly important), according to three outcome categories: pain, function, and structure.

Results

Participants identified 121 baseline characteristics. A rating ?7 points was assigned to 39 characteristics (e.g., age, depression, global knee pain, daily dose of pain killers, Kellgren-Lawrence grading); of these, 20 were related to pain, 15 to function, and 23 to structural outcomes. Global knee pain was the only baseline characteristic that fulfilled among experts the predefined consensus criteria.

Conclusions

Experts identified a large number of characteristics for describing patients with knee osteoarthritis. Disagreement and uncertainty prevailed over the relevance of these characteristics. Our findings justified further efforts to define appropriate, broadly acceptable sets of baseline characteristics for describing patients with knee osteoarthritis.

SUBMITTER: Wildi LM

PROVIDER: S-EPMC3882493 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature

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Publications

Relevant baseline characteristics for describing patients with knee osteoarthritis: results from a Delphi survey.

Wildi Lukas M LM Hensel Anita A Wertli Maria M Michel Beat A BA Steurer Johann J

BMC musculoskeletal disorders 20131230

<h4>Background</h4>Inclusion/exclusion criteria and baseline characteristics are essential for assessing the applicability of trial results to a given patient and the comparability of study populations for meta-analyses. This Delphi survey aimed to generate a set of baseline characteristics for describing patients with knee osteoarthritis enrolled in clinical studies.<h4>Methods</h4>Survey participants comprised clinical experts (n = 23; mean age 54 y; from 4 continents) that had authored at lea ...[more]

PMID: 24373617

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Project description:BackgroundRecently, there has been growing interest in providing more tailored, patient-centered care for the treatment of type 2 diabetes mellitus (T2DM). Yet it remains unclear which patient characteristics should be determined to guide such an approach. Therefore, the opinions of healthcare providers (HCP) and people with T2DM about relevant patient characteristics for estimating healthcare needs of people with T2DM were assessed and compared.MethodsTwo separate online Delphi studies were conducted according to the RAND-UCLA Appropriateness Method: one with HCPs (n?=?22) from Dutch primary and secondary care and one with people with T2DM treated in Dutch primary care (n?=?46). The relevance of patient characteristics for estimating healthcare needs, defined as the number of yearly consultations, was assessed on a 5-point Likert scale. Characteristics with a median of 4 or 5 and an interquartile range???1.5 were considered relevant with consensus. Participants were also asked to select the top 5 of most relevant patient characteristics. To determine the overall top 5, the mean relative importance score of each characteristic was calculated.ResultsIn two Delphi rounds, 28 and 15 patient characteristics were rated by HCPs and people with T2DM, respectively. Both HCPs and people with T2DM found health-related characteristics relevant for estimating healthcare needs of people with T2DM. However, HCPs preferred to estimate healthcare needs using person- and context-related characteristics. They ranked self-efficacy as the most relevant estimator. In contrast, people with T2DM were more in favor of health-related characteristics and ranked HbA1c as the most relevant estimator.ConclusionsThe findings show that there is discrepancy in opinions on relevant patient characteristics for estimating healthcare needs between HCPs and people with T2DM. To achieve more tailored, patient-centered care, it is important that both groups agree on the topics to be discussed during patient consultations.

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Dataset Information

Relevant baseline characteristics for describing patients with knee osteoarthritis: results from a Delphi survey.

Background

Methods

Results

Conclusions

Publications

Relevant baseline characteristics for describing patients with knee osteoarthritis: results from a Delphi survey.

Similar Datasets

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