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Phaeohyphomycotic dermatitis in a giant panda (Ailuropoda melanoleuca) caused by Cladosporium cladosporioides.


ABSTRACT: We report here a clinical case of phaeohyphomycosis in an 18-year-old male giant panda (Ailuropoda melanoleuca). Skin lesions on the giant panda disappeared following 2 months of treatment with ketoconazole. Three months after discontinuing the treatment, there was a clinical and mycological relapse. The disease progression was no longer responsive to ketoconazole. Microscopy and polymerase chain reaction (PCR) analysis revealed that the infection was caused by Cladosporium cladosporioides. A 4-month treatment regime with Itraconazole oral solution (700 mg per day) successfully terminated the infection.

SUBMITTER: Ma X 

PROVIDER: S-EPMC3885951 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Phaeohyphomycotic dermatitis in a giant panda (Ailuropoda melanoleuca) caused by Cladosporium cladosporioides.

Ma Xiaoping X   Gu Yu Y   Liu Xiaomin X   Li Desheng D   Ling Shanshan S   Hou Jiafa J   Wang Chengdong C   Cao Sanjie S   Huang Xiaobo X   Wen Xintian X   Ruan Jiaxue J   Dong Cao C   Li Changcheng C   Tong Yufei Y  

Medical mycology case reports 20130606


We report here a clinical case of phaeohyphomycosis in an 18-year-old male giant panda (Ailuropoda melanoleuca). Skin lesions on the giant panda disappeared following 2 months of treatment with ketoconazole. Three months after discontinuing the treatment, there was a clinical and mycological relapse. The disease progression was no longer responsive to ketoconazole. Microscopy and polymerase chain reaction (PCR) analysis revealed that the infection was caused by Cladosporium cladosporioides. A 4-  ...[more]

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