Ontology highlight
ABSTRACT:
SUBMITTER: Peppin JF
PROVIDER: S-EPMC3886382 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Peppin John F JF Pappagallo Marco M
Therapeutic advances in neurological disorders 20140101 1
The treatment of neuropathic pain is difficult. Oral pharmaceuticals have significant side effects, and treatment efficacy tends to be modest. The use of topical analgesics reduces the potential for systemic side effects and allows direct application of medications to the area of pain. The natural spicy substance, capsaicin, has historically been known for its topical use. Capsaicin, once applied to the skin, causes a brief initial sensitization followed by a prolonged desensitization of the loc ...[more]