Ontology highlight
ABSTRACT:
SUBMITTER: Pierce BL
PROVIDER: S-EPMC3887566 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Pierce Brandon L BL Tong Lin L Argos Maria M Gao Jianjun J Farzana Jasmine J Roy Shantanu S Paul-Brutus Rachelle R Rahaman Ronald R Rakibuz-Zaman Muhammad M Parvez Faruque F Ahmed Alauddin A Quasem Iftekhar I Hore Samar K SK Alam Shafiul S Islam Tariqul T Harjes Judith J Sarwar Golam G Slavkovich Vesna V Gamble Mary V MV Chen Yu Y Yunus Mohammad M Rahman Mahfuzar M Baron John A JA Graziano Joseph H JH Ahsan Habibul H
International journal of epidemiology 20131201 6
<h4>Background</h4>Arsenic exposure through drinking water is a serious global health issue. Observational studies suggest that individuals who metabolize arsenic efficiently are at lower risk for toxicities such as arsenical skin lesions. Using two single nucleotide polymorphisms(SNPs) in the 10q24.32 region (near AS3MT) that show independent associations with metabolism efficiency, Mendelian randomization can be used to assess whether the association between metabolism efficiency and skin lesi ...[more]