Ontology highlight
ABSTRACT:
SUBMITTER: Darnell RB
PROVIDER: S-EPMC3889695 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Neurons have their own systems for regulating RNA. Several multigene families encode RNA binding proteins (RNABPs) that are uniquely expressed in neurons, including the well-known neuron-specific markers ELAV and NeuN and the disease antigen NOVA. New technologies have emerged in recent years to assess the function of these proteins in vivo, and the answers are yielding insights into how and why neurons may regulate RNA in special ways-to increase cellular complexity, to localize messenger RNA ( ...[more]