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Nicotine modulation of information processing is not limited to input (attention) but extends to output (intention).

ABSTRACT: RATIONALE:Nicotine influences many cognitive processes, especially those requiring high attentional loads, yet the impact of nicotine on all aspects of information processing has not been well delineated. OBJECTIVE:The aim of the study was to determine the relative behavioral and functional effects of nicotine on dissociable aspects of information processing (i.e., selective attention and motor intention). METHODS:Adult smokers (N = 25) and healthy controls (N = 23) performed the intention/attention task (IAT) twice, during functional magnetic resonance imaging. The IAT assesses the relative differences in performance evoked by prime stimuli that provide information regarding either the correct hand with which to respond (i.e., intentional primes) or the likely location of a target stimulus (i.e., attentional primes). Smokers were scanned 2 h after nicotine (21 mg) or placebo patch placement. The order of nicotine and placebo sessions was randomized and counter-balanced. Controls were also scanned twice, with no patch placement in either session. RESULTS:While drug condition had no significant effect on reaction time, smokers were overall more accurate than controls. Moreover, nicotine significantly increased the response to intentional primes in brain regions known to mediate response readiness, e.g., inferior parietal lobe, supramarginal gyrus, and striatum. CONCLUSIONS:While limited to participant accuracy, these data suggest that the behavioral effects of nicotine in smokers are not only limited to information processing input (i.e., selective attention) but are also generalizable to output functions (i.e., motor intention). Moreover, nicotine's effects on intention appear to be mediated by a facilitation of function in brain regions associated with information processing output.

SUBMITTER: Rose EJ

PROVIDER: S-EPMC3890397 | biostudies-literature | 2010 May

REPOSITORIES: biostudies-literature

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Nicotine modulation of information processing is not limited to input (attention) but extends to output (intention).

Rose Emma J EJ Ross Thomas J TJ Kurup Pradeep K PK Stein Elliot A EA

Psychopharmacology 20100323 4

<h4>Rationale</h4>Nicotine influences many cognitive processes, especially those requiring high attentional loads, yet the impact of nicotine on all aspects of information processing has not been well delineated.<h4>Objective</h4>The aim of the study was to determine the relative behavioral and functional effects of nicotine on dissociable aspects of information processing (i.e., selective attention and motor intention).<h4>Methods</h4>Adult smokers (N = 25) and healthy controls (N = 23) perform ...[more]

PMID: 20309531

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Project description:Rapid development of intelligent information equipment accelerates the expansion of mobile social network. Speed of information spreading is gradually growing, there are lots of changes in the scale and mode of information spreading. But the basic communication network is not developed and not mature, when online information platforms breakdown sometimes it happens to be when important information appears. Therefore, the research is done to solve these occasion problems, help network information platform filter hot news and discuss the reason that hot news exists longer than other news in the Internet. In this paper, a multiple information propagation model incorporating both local information environment and people's limited attention is proposed based on Susceptible Infected Recovered (SIR) model. Two new concepts are introduced into the model: heat rate and popular rate, to measure the local information influence power and people's limited attention to information respectively, which are key factors determining node state transformation instead of fixed probability. In order to analyze the influence from limited attention, a situation is designed that several pieces of information are popular successively. The theoretical analysis shows that the early popular information gets more attention than the later popular information, and more attention makes it easier to spread. Besides, numerical simulation is conducted in both uniform network and scale-free network. The simulation results show that the early popular information is less vulnerable to the increase of information acceptance threshold and more sensitive to the decrease of information rejection threshold than the later popular information. Moreover, the model can also be used in the case of large amount of information transmission without adding too much complexity. Reasons are given in the research that the top hot news exists very much longer than the other ones, and latter news which have same influence as top news are hard to get the same focus. Meanwhile, results in the research can provide some ways for the other researches in the related fields. They also help related information platforms to filter and push news and referable strategies to maintain hot news.

Dataset Information

Nicotine modulation of information processing is not limited to input (attention) but extends to output (intention).

Publications

Nicotine modulation of information processing is not limited to input (attention) but extends to output (intention).

Similar Datasets

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