Ontology highlight
ABSTRACT:
SUBMITTER: Shigematsu H
PROVIDER: S-EPMC3896422 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Shigematsu Hiroaki H Kumagai Kenichi K Kobayashi Hiroshi H Eguchi Takanori T Kitaura Kazutaka K Suzuki Satsuki S Horikawa Tatsuya T Matsutani Takaji T Ogasawara Kouetsu K Hamada Yoshiki Y Suzuki Ryuji R
PloS one 20140120 1
Chromium (Cr) causes delayed-type hypersensitivity reactions possibly mediated by accumulating T cells into allergic inflamed skin, which are called irritants or allergic contact dermatitis. However, accumulating T cells during development of metal allergy are poorly characterized because a suitable animal model is not available. This study aimed to elucidate the skewing of T-cell receptor (TCR) repertoire and cytokine profiles in accumulated T cells in inflamed skin during elucidation of Cr all ...[more]