Ontology highlight
ABSTRACT:
SUBMITTER: Ahn HJ
PROVIDER: S-EPMC3897664 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Ahn Hak Jun HJ Kim Kang Il KI Hoan Nguyen Ngoc NN Kim Churl Ho CH Moon Eunpyo E Choi Kyeong Sook KS Yang Sang Sik SS Lee Jong-Soo JS
PloS one 20140121 1
The plasma jet has been proposed as a novel therapeutic method for cancer. Anticancer activity of plasma has been reported to involve mitochondrial dysfunction. However, what constituents generated by plasma is linked to this anticancer process and its mechanism of action remain unclear. Here, we report that the therapeutic effects of air plasma result from generation of reactive oxygen/nitrogen species (ROS/RNS) including H2O2, Ox, OH-, •O2, NOx, leading to depolarization of mitochondrial membr ...[more]