Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide.
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ABSTRACT:
SUBMITTER: Shin SR
PROVIDER: S-EPMC3898458 | biostudies-literature | 2013 Nov
REPOSITORIES: biostudies-literature
Publications
Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide.
Shin Su Ryon SR Aghaei-Ghareh-Bolagh Behnaz B Dang Tram T TT Topkaya Seda Nur SN Gao Xiguang X Yang Seung Yun SY Jung Sung Mi SM Oh Jong Hyun JH Dokmeci Mehmet R MR Tang Xiaowu Shirley XS Khademhosseini Ali A Khademhosseini Ali A
Advanced materials (Deerfield Beach, Fla.) 20130901 44
Incorporating graphene oxide inside GelMA hydrogels enhances their mechanical properties and reduces UV-induced cell damage while preserving their favorable characteristics for 3D cell encapsulation. NIH-3T3 fibroblasts encapsulated in GO-GelMA microgels demonstrate excellent cellular viability, proliferation, spreading, and alignment. GO reinforcement combined with a multi-stacking approach offers a facile engineering strategy for the construction of complex artificial tissues. ...[more]
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