Ontology highlight
ABSTRACT:
SUBMITTER: Stokes MG
PROVIDER: S-EPMC3898895 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Stokes Mark G MG Kusunoki Makoto M Sigala Natasha N Nili Hamed H Gaffan David D Duncan John J
Neuron 20130404 2
Cognitive flexibility is fundamental to adaptive intelligent behavior. Prefrontal cortex has long been associated with flexible cognitive function, but the neurophysiological principles that enable prefrontal cells to adapt their response properties according to context-dependent rules remain poorly understood. Here, we use time-resolved population-level neural pattern analyses to explore how context is encoded and maintained in primate prefrontal cortex and used in flexible decision making. We ...[more]