Ontology highlight
ABSTRACT:
SUBMITTER: Shen W
PROVIDER: S-EPMC3899311 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Shen Wenjing W Song Min M Liu Jie J Qiu Guangrong G Li Tianren T Hu Yanjie Y Liu Hongbo H
PloS one 20140122 1
MicroRNAs (miRNAs) important for posttranscriptional gene expression are involved in the initiation and progression of human cancer. In this study, we reported that miR-26a was over-expressed in human EOC specimens and the expression level of extracellular miR-26a in plasma can distinguish patients from healthy controls in EOC. Ectopic expression of miR-26a in ovarian cancer (OC) cells increased cell proliferation and clonal formation. This growth promoting effect of OC cell growth was mediated ...[more]