Ontology highlight
ABSTRACT:
SUBMITTER: Novak J
PROVIDER: S-EPMC3900797 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Novák Jan J Kružliak Peter P Bienertová-Vašků Julie J Slabý Ondřej O Novák Miroslav M
Theranostics 20140102 2
MicroRNAs (miRs) are small non-coding RNAs that negatively regulate gene expression by binding to the 3` untranslated regions (3`UTR) of their target mRNAs. MiRs were shown to play pivotal roles in tissue development and function and are also involved in the pathogenesis of various diseases including cancer. MicroRNA-206, which belongs to the group of so-called "myomiRs", is one of the most studied miRs thus far. In addition to being involved in skeletal muscle development and pathology, it has ...[more]