Ontology highlight
ABSTRACT:
SUBMITTER: Sassoli C
PROVIDER: S-EPMC3901134 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Sassoli Chiara C Zecchi-Orlandini Sandra S Formigli Lucia L
Cells 20121017 4
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) represent the leading candidate cell in tissue engineering and regenerative medicine. These cells can be easily isolated, expanded in vitro and are capable of providing significant functional benefits after implantation in the damaged muscle tissues. Despite their plasticity, the participation of BM-MSCs to new muscle fiber formation is controversial; in fact, emerging evidence indicates that their therapeutic effects occur without signs of ...[more]