Ontology highlight
ABSTRACT:
SUBMITTER: Ubink I
PROVIDER: S-EPMC3903062 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Ubink Inge I van der Sluis Pieter P Schipper Marguerite M Reerink Onne O Voest Emile E Borel-Rinkes Inne I Wijrdeman Harm H Vleggaar Frank F Agterof Marriete M Overkleeft Esther E Siersema Peter P van Hillegersberg Richard R Lolkema M P MP
The oncologist 20131212 1
<h4>Background</h4>Local and systemic recurrence are important sources of treatment failure following surgical resection of esophageal adenocarcinoma. We hypothesized that adding preoperative cetuximab and radiotherapy (cetux-RT) to perioperative chemotherapy would increase treatment efficacy with acceptable toxicity.<h4>Methods</h4>In this prospective phase II trial, patients were treated with three cycles of epirubicin, cisplatin, and capecitabine (ECX), followed by cetux-RT. After surgery wit ...[more]