Sex differences in the human peripheral blood transcriptome.
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ABSTRACT:
SUBMITTER: Jansen R
PROVIDER: S-EPMC3904696 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Publications
Sex differences in the human peripheral blood transcriptome.
Jansen Rick R Batista Sandra S Brooks Andrew I AI Tischfield Jay A JA Willemsen Gonneke G van Grootheest Gerard G Hottenga Jouke-Jan JJ Milaneschi Yuri Y Mbarek Hamdi H Madar Vered V Peyrot Wouter W Vink Jacqueline M JM Verweij Cor L CL de Geus Eco J C EJ Smit Johannes H JH Wright Fred A FA Sullivan Patrick F PF Boomsma Dorret I DI Penninx Brenda W J H BW
BMC genomics 20140117
<h4>Background</h4>Genomes of men and women differ in only a limited number of genes located on the sex chromosomes, whereas the transcriptome is far more sex-specific. Identification of sex-biased gene expression will contribute to understanding the molecular basis of sex-differences in complex traits and common diseases.<h4>Results</h4>Sex differences in the human peripheral blood transcriptome were characterized using microarrays in 5,241 subjects, accounting for menopause status and hormonal ...[more]
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