Ontology highlight
ABSTRACT:
SUBMITTER: Munera D
PROVIDER: S-EPMC3905246 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Munera Diana D Ritchie Jennifer M JM Hatzios Stavroula K SK Bronson Rod R Fang Gang G Schadt Eric E EE Davis Brigid M BM Waldor Matthew K MK
Nature communications 20140101
The outbreak of diarrhoea and haemolytic uraemic syndrome that occurred in Germany in 2011 was caused by a Shiga toxin-producing enteroaggregative Escherichia coli (EAEC) strain. The strain was classified as EAEC owing to the presence of a plasmid (pAA) that mediates a characteristic pattern of aggregative adherence on cultured cells, the defining feature of EAEC that has classically been associated with virulence. Here we describe an infant rabbit-based model of intestinal colonization and diar ...[more]