Ontology highlight
ABSTRACT:
SUBMITTER: Gulati A
PROVIDER: S-EPMC3910010 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
CPT: pharmacometrics & systems pharmacology 20140108
Bridging systems biology and pharmacokinetics-pharmacodynamics has resulted in models that are highly complex and complicated. They usually contain large numbers of states and parameters and describe multiple input-output relationships. Based on any given data set relating to a specific input-output process, it is possible that some states of the system are either less important or have no influence at all. In this study, we explore a simplification of a systems pharmacology model of the coagula ...[more]