Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC3910569 | biostudies-literature | 2014 Jan
REPOSITORIES: biostudies-literature
Wu Jian J Tian Linjie L Yu Xiao X Pattaradilokrat Sittiporn S Li Jian J Wang Mingjun M Yu Weishi W Qi Yanwei Y Zeituni Amir E AE Nair Sethu C SC Crampton Steve P SP Orandle Marlene S MS Bolland Silvia M SM Qi Chen-Feng CF Long Carole A CA Myers Timothy G TG Coligan John E JE Wang Rongfu R Su Xin-zhuan XZ
Proceedings of the National Academy of Sciences of the United States of America 20140113 4
Malaria infection triggers vigorous host immune responses; however, the parasite ligands, host receptors, and the signaling pathways responsible for these reactions remain unknown or controversial. Malaria parasites primarily reside within RBCs, thereby hiding themselves from direct contact and recognition by host immune cells. Host responses to malaria infection are very different from those elicited by bacterial and viral infections and the host receptors recognizing parasite ligands have been ...[more]