Ontology highlight
ABSTRACT:
SUBMITTER: Horvatits T
PROVIDER: S-EPMC3910760 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Horvatits Thomas T Kitzberger Reinhard R Drolz Andreas A Zauner Christian C Jäger Walter W Böhmdorfer Michaela M Kraff Stefanie S Fritsch Achim A Thalhammer Florian F Fuhrmann Valentin V Schenk Peter P
Antimicrobial agents and chemotherapy 20131021 1
Ganciclovir is an antiviral agent that is frequently used in critically ill patients with cytomegalovirus (CMV) infections. Continuous venovenous hemodiafiltration (CVVHDF) is a common extracorporeal renal replacement therapy in intensive care unit patients. The aim of this study was to investigate the pharmacokinetics of ganciclovir in anuric patients undergoing CVVHDF. Population pharmacokinetic analysis was performed for nine critically ill patients with proven or suspected CMV infection who ...[more]