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Fatal empyema thoracis caused by Schizophyllum commune with cross-reactive cryptococcal antigenemia.

ABSTRACT: We report a fatal case of Schizophyllum commune empyema thoracis with cross-reactive cryptococcal antigenemia. In vitro testing confirmed the ability of the fungus to cause a positive cryptococcal antigen latex agglutination system (CALAS) test result. Such a result may lead to delay in diagnosis and treatment, as most strains of S. commune are resistant to fluconazole.

SUBMITTER: Chan JF

PROVIDER: S-EPMC3911328 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Fatal empyema thoracis caused by Schizophyllum commune with cross-reactive cryptococcal antigenemia.

Chan Jasper F W JF Teng Jade L L JL Li Iris W S IW Wong Sally C Y SC Leung Sally S M SS Ho Po-On PO To Kelvin K W KK Lau Susanna K P SK Woo Patrick C Y PC Yuen Kwok-Yung KY

Journal of clinical microbiology 20131113 2

We report a fatal case of Schizophyllum commune empyema thoracis with cross-reactive cryptococcal antigenemia. In vitro testing confirmed the ability of the fungus to cause a positive cryptococcal antigen latex agglutination system (CALAS) test result. Such a result may lead to delay in diagnosis and treatment, as most strains of S. commune are resistant to fluconazole. ...[more]

PMID: 24478514

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